Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.68 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | TERT | O14746 | 2/20 | 0.65 |
| ▸ | PPARG | P37231 | 3/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA4 | P22748 | 1/20 | 0.62 |
| ▸ | CA7 | P43166 | 1/20 | 0.62 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.62 |
| ▸ | PIM1 | P11309 | 1/20 | 0.62 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.62 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.62 |
| ▸ | PPARD | Q03181 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848130 | 0.90 | DHODH (0.73) | DHODHKDM4EMEN1PKMKMT2A | |
| SCHEMBL18120563 | 0.88 | DHODH (1.00) | DHODHKDM4EMEN1PKMKMT2A | |
| SCHEMBL7164649 | 0.88 | DHODH (0.64) | DHODHKDM4EMEN1PKMKMT2A | |
| SCHEMBL16211079 | 0.86 | NPC1 (0.64) | DHODHKDM4ENR1H4SLC16A3NPC1 | |
| SCHEMBL6408811 | 0.86 | MEN1 (0.64) | DHODHKDM4EMEN1PKMKMT2A | |
| SCHEMBL7237031 | 0.86 | SUCNR1 (0.73) | DHODHKDM4EMEN1PKMKMT2A | |
| SCHEMBL14441241 | 0.85 | KDM4E (0.64) | DHODHKDM4EMEN1PKMKMT2A | |
| SCHEMBL2028671 | 0.85 | DHODH (0.86) | DHODHMEN1PKMKMT2ANPC1 | |
| SCHEMBL6357745 | 0.84 | DHODH (0.78) | DHODHKDM4EMEN1KMT2ANR1H4 | |
| SCHEMBL1307456 | 0.84 | GRIK1 (0.67) | DHODHKDM4EMEN1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1907960-A | Anthranilic acid derivatives | TEIJIN LTD (JP) | 2007-02-07 | — | — | CN | disclosed |
| CN-1081623-C | Benzene derivatives | TEIJIN LTD (JP) | 2002-03-27 | — | — | CN | disclosed |
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |
| CN-1048239-C | Naphthalene deriv. | TEIJIN LTD (JP) | 2000-01-12 | — | — | CN | disclosed |
| EP-0763523-B1 | NAPHTHALENE DERIVATIVE | TEIJIN LTD (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5945450-A | ANTIALLERGENS | TEIJIN LIMITED (JP) | 1999-08-31 | — | — | US | disclosed |
| US-5808144-A | ANTIALLERGENS | TEIJIN LIMITED (JP) | 1998-09-15 | — | — | US | disclosed |
| CN-1173169-A | Benzene derivatives | TEIJIN LTD (JP) | 1998-02-11 | — | — | CN | disclosed |
| EP-0806412-A1 | BENZENE DERIVATIVES | TEIJIN LIMITED (JP) | 1997-11-12 | — | — | EP | disclosed |
| CN-1153511-A | Naphthalene deriv. | TEIJIN LTD (JP) | 1997-07-02 | — | — | CN | disclosed |
| EP-0763523-A1 | NAPHTHALENE DERIVATIVE | TEIJIN LIMITED (JP) | 1997-03-19 | — | — | EP | disclosed |