Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 17/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3093673 | 0.81 | MIF (0.54) | MIFNOTUMF10 | |
| SCHEMBL3087805 | 0.80 | MIF (0.55) | MIFNOTUMF10 | |
| SCHEMBL1097349 | 0.79 | MIF (0.52) | MIFNOTUMF10 | |
| SCHEMBL3091423 | 0.78 | MIF (0.62) | MIFNOTUMF10 | |
| SCHEMBL1106557 | 0.77 | MIF (0.61) | MIFNOTUM | |
| SCHEMBL1095716 | 0.77 | F10 (0.56) | MIFF10 | |
| SCHEMBL8049656 | 0.76 | LMNA (0.44) | F10 | |
| SCHEMBL1096549 | 0.76 | MIF (0.48) | MIFNOTUMF10 | |
| SCHEMBL3090082 | 0.76 | MIF (0.60) | MIFNOTUM | |
| SCHEMBL3082953 | 0.76 | MIF (0.59) | MIFNOTUMF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009063029-A2 | SUBSTITUTED AMIDES, MANUFACTURING AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-22 | — | — | WO | disclosed |