Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 19/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044210 | 0.76 | MIF (0.51) | F10 | |
| SCHEMBL12410715 | 0.73 | F10 (0.71) | F10 | |
| SCHEMBL2182585 | 0.71 | F10 (0.68) | F10 | |
| SCHEMBL3032983 | 0.71 | KMT2A (0.48) | LMNAMAPK1KMT2AF10 | |
| SCHEMBL8045834 | 0.70 | F10 (0.67) | F10 | |
| SCHEMBL5482637 | 0.69 | LMNA (0.48) | LMNAMAPK1KMT2AF10 | |
| SCHEMBL5474672 | 0.69 | F10 (0.47) | LMNAMAPK1KMT2AF10 | |
| SCHEMBL5475952 | 0.68 | F10 (0.45) | LMNAMAPK1KMT2AF10 | |
| SCHEMBL3091122 | 0.67 | MIF (0.53) | F10 | |
| SCHEMBL1277697 | 0.67 | HPGD (0.45) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009063029-A2 | SUBSTITUTED AMIDES, MANUFACTURING AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-22 | — | — | WO | disclosed |