Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044890 | 0.88 | ATM (0.47) | ALDH1A1KMT2AMEN1THRBLMNA | |
| SCHEMBL8048154 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1LMNATSHR | |
| SCHEMBL8043474 | 0.79 | MEN1 (0.53) | ALDH1A1KMT2AMEN1LMNAPOLB | |
| SCHEMBL8034279 | 0.78 | HDAC6 (0.45) | ALDH1A1KMT2AMEN1THRBLMNA | |
| SCHEMBL8052363 | 0.78 | TSHR (0.42) | ALDH1A1KMT2AMEN1THRBLMNA | |
| SCHEMBL8033099 | 0.78 | MEN1 (0.43) | ALDH1A1KMT2AMEN1THRBLMNA | |
| SCHEMBL8043606 | 0.77 | MEN1 (0.42) | ALDH1A1KMT2AMEN1LMNAPOLB | |
| SCHEMBL8048610 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1THRBLMNA | |
| SCHEMBL8048226 | 0.76 | MEN1 (0.45) | ALDH1A1KMT2AMEN1THRBLMNA | |
| SCHEMBL8046339 | 0.75 | POLB (0.41) | ALDH1A1KMT2AMEN1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |