Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | FBP1 | P09467 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045795 | 0.87 | ATM (0.48) | ALDH1A1NPC1RAB9AHSD17B10LMNA | |
| SCHEMBL8045096 | 0.78 | PDPK1 (0.51) | ALDH1A1NPC1POLBKMT2AMEN1 | |
| SCHEMBL8048705 | 0.77 | FBP1 (0.46) | ALDH1A1NPC1RAB9ATSHRKMT2A | |
| SCHEMBL8046775 | 0.77 | FBP1 (0.42) | ALDH1A1TSHRFBP1PDK1 | |
| SCHEMBL8034366 | 0.76 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9AABL1HSD17B10 | |
| SCHEMBL8044299 | 0.76 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9AHSD17B10LMNA | |
| SCHEMBL8051741 | 0.75 | GSK3B (0.39) | ALDH1A1LMNATSHRAPEX1L3MBTL1 | |
| SCHEMBL8048154 | 0.75 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9ALMNATSHR | |
| SCHEMBL8031756 | 0.75 | FBP1 (0.44) | ALDH1A1NPC1RAB9ALMNATSHR | |
| SCHEMBL8042143 | 0.75 | POLB (0.42) | ALDH1A1HSD17B10TSHRPOLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |