Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 3/20 | 0.43 |
| ▸ | CDC25A | P30304 | 2/20 | 0.43 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042393 | 0.82 | ALPG (0.40) | ALPGCDC25ACDC25BLMNAHTT | |
| SCHEMBL8047548 | 0.81 | NPSR1 (0.54) | LMNAHTTKDM4ECYP3A4ALDH1A1 | |
| SCHEMBL8043271 | 0.80 | ALPG (0.45) | ALPGCDC25ACDC25BLMNAHTT | |
| SCHEMBL8042199 | 0.80 | ALPG (0.46) | ALPGCDC25ACDC25BLMNAHTT | |
| SCHEMBL8033784 | 0.80 | ALPG (0.42) | ALPGCDC25ACDC25BLMNAHTT | |
| SCHEMBL8043642 | 0.80 | MAPT (0.52) | ALPGCDC25ACDC25BLMNAHTT | |
| SCHEMBL8045447 | 0.80 | POLA1 (0.41) | ALPGCDC25ACDC25BLMNAHTT | |
| SCHEMBL8033695 | 0.79 | ALPG (0.44) | ALPGCDC25ACDC25BLMNAHTT | |
| SCHEMBL8048718 | 0.79 | RPA1 (0.50) | HTTKDM4ECYP3A4ALDH1A1MEN1 | |
| SCHEMBL8032437 | 0.78 | ALPG (0.42) | ALPGCDC25ACDC25BLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |