Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8047063 | 0.85 | TSHR (0.51) | MAPTHSD17B10KDM4EHPGDTSHR | |
| SCHEMBL8042116 | 0.81 | SMN1; SMN2 (0.41) | MAPTKDM4ETSHRALDH1A1MAPK1 | |
| SCHEMBL8032654 | 0.79 | RPA1 (0.51) | RPA1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL8048173 | 0.79 | MAPT (0.36) | MAPTHSD17B10HPGDTSHRALDH1A1 | |
| SCHEMBL8044342 | 0.79 | ALPG (0.43) | MAPTKDM4EHPGDTSHRALDH1A1 | |
| SCHEMBL8044772 | 0.79 | MAPT (0.38) | MAPTALDH1A1USP7NPSR1MEN1 | |
| SCHEMBL8049971 | 0.79 | RPA1 (0.49) | RPA1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL8044969 | 0.78 | ALDH1A1 (0.45) | MAPTKDM4EHPGDALDH1A1HDAC6 | |
| SCHEMBL8042509 | 0.78 | HSD17B10 (0.47) | MAPTHSD17B10KDM4EHPGDTSHR | |
| SCHEMBL8044131 | 0.78 | RPA1 (0.44) | RPA1MAPTHSD17B10KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |