Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.76 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6724132 | 0.86 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8044560 | 0.86 | PTGS2 (0.66) | PTGS2PTGS1SMN1; SMN2 | |
| SCHEMBL5715568 | 0.84 | PTGS2 (0.69) | PTGS2SMN1; SMN2ERN1 | |
| SCHEMBL8974723 | 0.84 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL6725713 | 0.84 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL213834 | 0.84 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL12326172 | 0.82 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL14499498 | 0.81 | PTGS2 (0.71) | PTGS2PTGS1SMN1; SMN2ERN1 | |
| SCHEMBL7500687 | 0.81 | PTGS2 (0.67) | PTGS2PTGS1SMN1; SMN2 | |
| SCHEMBL9117120 | 0.81 | PTGS2 (1.00) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794942-B1 | SUBSTITUTED BIPHENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2000-05-31 | — | — | EP | claimed |