Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 3/20 | 0.60 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.60 |
| ▸ | CDK9 | P50750 | 2/20 | 0.60 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.60 |
| ▸ | CDK14 | O94921 | 7/20 | 0.57 |
| ▸ | CCNY | Q8ND76 | 7/20 | 0.57 |
| ▸ | CDK2 | P24941 | 6/20 | 0.57 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.57 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.57 |
| ▸ | CDK4 | P11802 | 2/20 | 0.57 |
| ▸ | CDK1 | P06493 | 2/20 | 0.57 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.57 |
| ▸ | CASK | O14936 | 1/20 | 0.57 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.57 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.57 |
| ▸ | MAK | P20794 | 1/20 | 0.57 |
| ▸ | CDK11B | P21127 | 1/20 | 0.57 |
| ▸ | CCND1 | P24385 | 1/20 | 0.57 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.57 |
| ▸ | CCND3 | P30281 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| At-7519 SCHEMBL955568 | 0.94 | CDK5 (0.67) | CDK5CCNT1CDK9CDK5R1CDK14 | |
| At-7519 SCHEMBL953647 | 0.93 | CDK5 (0.66) | CDK5CCNT1CDK9CDK5R1CDK14 | |
| At-7519 SCHEMBL31046986 | 0.93 | CDK5 (0.66) | CDK5CCNT1CDK9CDK5R1CDK14 | |
| At-7519 SCHEMBL1069453 | 0.92 | CDK5 (0.62) | CDK5CCNT1CDK9CDK5R1CDK14 | |
| At-7519 SCHEMBL16318377 | 0.91 | CDK5 (0.61) | CDK5CCNT1CDK9CDK5R1CDK14 | |
| At-7519 SCHEMBL1072294 | 0.91 | CDK5 (0.61) | CDK5CCNT1CDK9CDK5R1CDK14 | |
| SCHEMBL1286740 | 0.89 | CDK2 (0.67) | CDK5CCNT1CDK9CDK5R1CDK14 | |
| SCHEMBL13993660 | 0.86 | LMNA (0.46) | CDK5CCNT1CDK9CDK5R1CDK14 | |
| SCHEMBL1286739 | 0.83 | CDK5 (0.53) | CDK5CCNT1CDK9CDK5R1CDK14 | |
| SCHEMBL954758 | 0.83 | CDK2 (0.64) | CDK5CCNT1CDK9CDK5R1CDK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230330258-A1 | CONJUGATES COMPRISING A PHOSPHORUS (V) AND A DRUG MOIETY | TUBULIS GMBH (DE) | 2023-10-19 | — | — | US | disclosed |
| WO-2009061345-A2 | TARGETING CDK4 AND CDK6 IN CANCER THERAPY | CORNELL RESEARCH FOUNDATION, INC. (US) | 2009-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230330258-A1 | CONJUGATES COMPRISING A PHOSPHORUS (V) AND A DRUG MOIETY | CALCR, BCR, PTH1R | CDK5 2396/4885CCNT1 3176/4885CDK9 1621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.