Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | CASP2 | P42575 | 1/20 | 0.49 |
| ▸ | EYA2 | O00167 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9654139 | 1.00 | TDP1 (0.50) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL1419591 | 0.98 | CASP2 (0.51) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL1420133 | 0.98 | CASP2 (0.51) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL2029653 | 0.98 | CASP2 (0.51) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL1419654 | 0.98 | CASP2 (0.51) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL2027019 | 0.98 | CASP2 (0.51) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL1419852 | 0.98 | CASP2 (0.51) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL1419840 | 0.98 | CASP2 (0.51) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL2029786 | 0.98 | CASP2 (0.51) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL1419475 | 0.98 | CASP2 (0.51) | TDP1KDM4ELMNACHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070009442-A1 | Macrocyclic metal complexes and their use for the production of conjugates with biomolecules | SCHERING AG (DE) | 2007-01-11 | — | — | US | disclosed |
| US-6080785-A | REACTING A ALKYLNEDI-PRIMARY AMINE COMPOUND WITH A PROTECTIVE GROUP SUCH AS TRIFLUOROACETYL OR BENZYL GROUP REAGENT TO FORM AN INTERMEDIATE, REACTING THE INTERMEDIATE WITH HALOACETIC TERT-BYTYL ESTER TO FORM ESTER GROUPS, DEPROTECTING | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-06-27 | — | — | US | disclosed |
| EP-0871608-B1 | Monofunctionalised EDTA-, DTPA- and TTHA-Derivatives and their use for the preparation of a diagnoctic or therapeutic medicine | SCHERING AG (DE) | 2000-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070009442-A1 | Macrocyclic metal complexes and their use for the production of conjugates with biomolecules | CA13, MPI, CA14 | TDP1 4513/4885KDM4E 3959/4885LMNA 4252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.