Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2029653 | 1.00 | CASP2 (0.51) | CASP2NAAATDP1KDM4ELMNA | |
| SCHEMBL9655480 | 1.00 | CASP2 (0.51) | CASP2NAAATDP1KDM4ELMNA | |
| SCHEMBL1420133 | 1.00 | CASP2 (0.51) | CASP2NAAATDP1KDM4ELMNA | |
| SCHEMBL1419815 | 1.00 | CASP2 (0.51) | CASP2NAAATDP1KDM4ELMNA | |
| SCHEMBL1419654 | 1.00 | CASP2 (0.51) | CASP2NAAATDP1KDM4ELMNA | |
| SCHEMBL2029786 | 1.00 | CASP2 (0.51) | CASP2NAAATDP1KDM4ELMNA | |
| SCHEMBL1419475 | 1.00 | CASP2 (0.51) | CASP2NAAATDP1KDM4ELMNA | |
| SCHEMBL1419852 | 1.00 | CASP2 (0.51) | CASP2NAAATDP1KDM4ELMNA | |
| SCHEMBL1419840 | 1.00 | CASP2 (0.51) | CASP2NAAATDP1KDM4ELMNA | |
| SCHEMBL1419591 | 1.00 | CASP2 (0.51) | CASP2NAAATDP1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3302434-B1 | NANOPARTICLES | KING S COLLEGE LONDON (GB) | 2025-01-29 | — | — | EP | claimed |
| US-20110130327-A1 | Multi-Arm Amines and Uses Thereof | MARINA BIOTECH, INC. (US) | 2011-06-02 | — | — | US | claimed |
| US-10702612-B2 | Conjugated polymer-based nanoprobe and preparation method and application thereof | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2020-07-07 | — | — | US | disclosed |
| US-20140234223-A1 | NANOEMULSIONS AND USE THEREOF AS CONTRAST AGENTS | GUERBET (FR) | 2014-08-21 | — | — | US | disclosed |
| WO-2013045333-A1 | NANOEMULSIONS AND USE THEREOF AS CONTRAST AGENTS | GUERBET (FR) | 2013-04-04 | — | — | WO | disclosed |
| WO-2012084981-A1 | CHELATE NANOEMULSION FOR MRI | GUERBET (FR) | 2012-06-28 | — | — | WO | disclosed |
| EP-1806350-B1 | Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents | BRACCO INT BV (NL) | 2010-01-06 | — | — | EP | disclosed |
| EP-1806350-A2 | Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents | BRACCO International B.V. (NL) | 2007-07-11 | — | — | EP | disclosed |
| US-6652834-B2 | Tensioactive properties, long lasting activity in the blood pool | BRACCO INTERNATIONAL B.V. (NL) | 2003-11-25 | — | — | US | disclosed |
| US-20020098152-A1 | Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents | BRACCO INTERNATIONAL B.V. | 2002-07-25 | — | — | US | disclosed |
| US-6342598-B1 | BLOOD-POOL CONTRAST AGENTS OF OUTSTANDING LONG LIFE IN CIRCULATION | BRACCO INTERNATIONAL B.V. (NL) | 2002-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10702612-B2 | Conjugated polymer-based nanoprobe and preparation method and application thereof | CD69, MYD88, VEGFA | CASP2 2641/4885NAAA 2032/4885TDP1 4356/4885 |
| US-20020098152-A1 | Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents | SLC39A14, HAMP, PICALM | CASP2 4719/4885NAAA 692/4885TDP1 3409/4885 |
| US-20110130327-A1 | Multi-Arm Amines and Uses Thereof | SNRPE, SNRPA, ADAR | CASP2 3037/4885NAAA 997/4885TDP1 645/4885 |
| US-20140234223-A1 | NANOEMULSIONS AND USE THEREOF AS CONTRAST AGENTS | PHOSPHO1, SGMS1, FABP7 | CASP2 3424/4885NAAA 519/4885TDP1 4103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.