Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044720 | 0.85 | PDK1 (0.45) | ALDH1A1HPGDKDM4ECYP1A2CYP2C9 | |
| SCHEMBL8042708 | 0.85 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4ECYP1A2CYP2C9 | |
| SCHEMBL8042974 | 0.85 | KDM4E (0.52) | ALDH1A1HPGDKDM4ECYP1A2CYP2C9 | |
| SCHEMBL8051920 | 0.81 | TSHR (0.51) | ALDH1A1HPGDKDM4ECYP1A2CYP2C9 | |
| SCHEMBL8043083 | 0.81 | HTT (0.43) | ALDH1A1HPGDKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL8051030 | 0.81 | HTT (0.43) | ALDH1A1HPGDMAPTSMN1; SMN2HTT | |
| SCHEMBL8044446 | 0.81 | KMT2A (0.41) | ALDH1A1HPGDKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL8051559 | 0.81 | KDM4E (0.45) | ALDH1A1HPGDKDM4ECYP1A2MAPT | |
| SCHEMBL8046377 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4ECYP1A2CYP2C9 | |
| SCHEMBL8043930 | 0.79 | KMT2A (0.44) | ALDH1A1HPGDKDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |