Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041642 | 0.86 | PPARG (0.49) | PPARGPPARAKDM4ETHRBTDP1 | |
| SCHEMBL218320 | 0.85 | THRB (0.46) | PPARGPPARAKDM4ETHRBALDH1A1 | |
| SCHEMBL23581933 | 0.83 | MAPT (0.52) | PPARGPPARAMAPTPKMSMN1; SMN2 | |
| SCHEMBL14113634 | 0.83 | AKR1C3 (0.43) | THRBTDP1MAPTL3MBTL1CYP1A2 | |
| SCHEMBL14182067 | 0.82 | THRB (0.43) | PPARGPPARAKDM4ETHRBALDH1A1 | |
| SCHEMBL14113638 | 0.82 | MAPT (0.43) | PPARGPPARAKDM4ETHRBALDH1A1 | |
| SCHEMBL1218505 | 0.81 | MAPT (0.45) | PPARGPPARAKDM4ETHRBTDP1 | |
| SCHEMBL23581937 | 0.81 | RXRA (0.47) | THRBMAPT | |
| SCHEMBL28244460 | 0.80 | THRB (0.48) | PPARGPPARAKDM4ETHRBALDH1A1 | |
| SCHEMBL11966995 | 0.79 | MAPT (0.42) | PPARGPPARATHRBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | claimed |
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | disclosed |