Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045199 | 0.93 | HDAC1 (0.38) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL8035061 | 0.91 | AHR (0.39) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL8050153 | 0.88 | HDAC1 (0.36) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL8049803 | 0.85 | HDAC1 (0.47) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL8052938 | 0.85 | HDAC1 (0.35) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL8049785 | 0.81 | HDAC1 (0.37) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL8047275 | 0.80 | AHR (0.39) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL8047362 | 0.79 | CYSLTR2 (0.46) | CYSLTR1MAPTKMT2ACYSLTR2 | |
| SCHEMBL8044655 | 0.79 | CYP3A4 (0.43) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL8049747 | 0.79 | CYP3A4 (0.43) | HDAC1HDAC8HDAC2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749957-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-04-26 | — | — | EP | disclosed |
| EP-0749957-A1 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-12-27 | — | — | EP | disclosed |