Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044839 | 0.91 | CYSLTR2 (0.45) | CYSLTR2CYSLTR1KMT2AMEN1PRNP | |
| SCHEMBL8049575 | 0.91 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1GAAKMT2AMEN1 | |
| SCHEMBL8050153 | 0.85 | HDAC1 (0.36) | — | |
| SCHEMBL8049803 | 0.83 | HDAC1 (0.47) | — | |
| SCHEMBL8052660 | 0.83 | PPARG (0.43) | CYSLTR2CYSLTR1GAAMAPTCNR2 | |
| SCHEMBL8046084 | 0.83 | CYSLTR2 (0.42) | CYSLTR2CYSLTR1KMT2AMEN1PRNP | |
| SCHEMBL8044917 | 0.79 | HDAC1 (0.36) | CYSLTR2CYSLTR1KMT2AMAPT | |
| SCHEMBL8045031 | 0.77 | MMP3 (0.45) | PRNP | |
| SCHEMBL8047275 | 0.76 | AHR (0.39) | KMT2AMEN1PRNPMAPT | |
| SCHEMBL8049785 | 0.76 | HDAC1 (0.37) | CYSLTR2CYSLTR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749957-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5891916-A | ANTINEUROGEGERATIVE AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0749957-A1 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-12-27 | — | — | EP | disclosed |