Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049785 | 0.92 | HDAC1 (0.37) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL8047275 | 0.92 | AHR (0.39) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL8044917 | 0.88 | HDAC1 (0.36) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL8049803 | 0.85 | HDAC1 (0.47) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL8047362 | 0.85 | CYSLTR2 (0.46) | — | |
| SCHEMBL8045910 | 0.85 | HDAC1 (0.35) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL8035061 | 0.81 | AHR (0.39) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL8045199 | 0.80 | HDAC1 (0.38) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL8045031 | 0.79 | MMP3 (0.45) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL8045183 | 0.78 | OPRM1 (0.43) | HDAC6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749957-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-04-26 | — | — | EP | disclosed |
| EP-0749957-A1 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-12-27 | — | — | EP | disclosed |