SCHEMBL8044985

SCHEMBL8044985

CCCCCCOc1ccc(C(=O)O)c(-c2ccc(CCCCC)cc2)c1

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 5/20 0.66
RARB P10826 12/20 0.59
RARA P10276 2/20 0.58
RARG P13631 1/20 0.58
PPARA Q07869 2/20 0.53
PPARG P37231 1/20 0.53
MEN1 O00255 1/20 0.52
ALDH1A1 P00352 1/20 0.52
MAPT P10636 1/20 0.52
MTOR P42345 1/20 0.52
KMT2A Q03164 1/20 0.52
MCL1 Q07820 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7981006 1.00 PTPN11 (0.66) PTPN11RARBRARARARGPPARA
SCHEMBL9193021 1.00 PTPN11 (0.66) PTPN11RARBRARARARGPPARA
SCHEMBL9619553 1.00 PTPN11 (0.66) PTPN11RARBRARARARGPPARA
SCHEMBL9501744 0.99 PTPN11 (0.64) PTPN11RARBRARARARGPPARA
SCHEMBL9485504 0.93 RARB (0.62) PTPN11RARBRARARARGMEN1
SCHEMBL11522282 0.92 PTPN11 (0.72) PTPN11RARBRARAMCL1
SCHEMBL11133724 0.91 PTPN11 (0.61) PTPN11RARBRARARARGPPARA
SCHEMBL11138404 0.91 PTPN11 (0.61) PTPN11RARBRARARARGPPARA
SCHEMBL8912209 0.91 PTPN11 (0.56) PTPN11RARBRARARARGMEN1
SCHEMBL9485538 0.91 PTPN11 (0.70) PTPN11RARBRARAALDH1A1MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11497687-B2 Chromic compositions TheUnseen Limited (GB) 2022-11-15 US disclosed
US-20200206096-A1 Chromic Compositions TheUnseen Limited (GB) 2020-07-02 US disclosed
EP-3641893-A1 CHROMIC COMPOSITIONS Theunseen Limited (GB) 2020-04-29 EP disclosed
CN-110997070-A Color-changing composition 泽安西恩有限公司 2020-04-10 CN disclosed
WO-2018234530-A1 CHROMIC COMPOSITIONS THEUNSEEN (GB) 2018-12-27 WO disclosed
EP-0700982-B1 A liquid crystal composition and a liquid crystal display element using the same CHISSO CORP (JP) 2000-04-26 EP disclosed
EP-0700982-A1 A liquid crystal composition and a liquid crystal display element using the same Chisso Corporation (JP) 1996-03-13 EP disclosed
EP-0471046-A1 COLOURANT MERCK PATENT GmbH (DE) 1992-02-19 EP disclosed
WO-1991013125-A2 COLOURANT MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-09-05 WO disclosed
EP-0423293-A1 DECORATIVE COMPOSITION. MERCK PATENT GMBH (DE) 1991-04-24 EP disclosed
WO-1990013282-A2 DECORATIVE COMPOSITION MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-11-15 WO disclosed