SCHEMBL9501744

SCHEMBL9501744

CCCCCOc1ccc(C(=O)O)c(-c2ccc(CCCCC)cc2)c1

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 5/20 0.64
RARB P10826 12/20 0.57
RARA P10276 2/20 0.56
RARG P13631 1/20 0.56
MCL1 Q07820 1/20 0.53
PPARA Q07869 2/20 0.51
PPARG P37231 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9193021 0.99 PTPN11 (0.66) PTPN11RARBRARARARGMCL1
SCHEMBL9619553 0.99 PTPN11 (0.66) PTPN11RARBRARARARGMCL1
SCHEMBL7981006 0.99 PTPN11 (0.66) PTPN11RARBRARARARGMCL1
SCHEMBL8044985 0.99 PTPN11 (0.66) PTPN11RARBRARARARGMCL1
SCHEMBL8912209 0.92 PTPN11 (0.56) PTPN11RARBRARARARGMCL1
SCHEMBL11521312 0.92 PTPN11 (0.70) PTPN11RARBRARAMCL1
SCHEMBL9485504 0.92 RARB (0.62) PTPN11RARBRARARARG
SCHEMBL8914026 0.91 PTPN11 (0.54) PTPN11RARBRARARARGMCL1
SCHEMBL11522282 0.91 PTPN11 (0.72) PTPN11RARBRARAMCL1
SCHEMBL11139894 0.91 PTPN11 (0.68) PTPN11RARBRARAMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4140016-A CHOLESTERIC LIQUID CRYSTAL THERMOMETERS, BENZOIC ESTER DERIVATIVES BECTON, DICKINSON AND COMPANY (US) 1979-02-20 US claimed
US-11497687-B2 Chromic compositions TheUnseen Limited (GB) 2022-11-15 US disclosed
US-20200206096-A1 Chromic Compositions TheUnseen Limited (GB) 2020-07-02 US disclosed
EP-3641893-A1 CHROMIC COMPOSITIONS Theunseen Limited (GB) 2020-04-29 EP disclosed
CN-110997070-A Color-changing composition 泽安西恩有限公司 2020-04-10 CN disclosed
WO-2018234530-A1 CHROMIC COMPOSITIONS THEUNSEEN (GB) 2018-12-27 WO disclosed
EP-0187768-B1 LIQUID CRYSTAL TEMPERATURE SENSOR AND MATERIALS FERGASON JAMES L (US) 1993-11-03 EP disclosed
EP-0423293-B1 DECORATIVE COMPOSITION MERCK PATENT GmbH (DE) 1993-04-21 EP disclosed
US-5130828-A Liquid crystal temperature sensor and materials MANCHESTER R&D PARTNERSHIP (US) 1992-07-14 US disclosed
US-4884877-A Liquid crystal temperature sensor and materials utilizing microencapsulated liquid crystal MANCHESTER R & D PARTNERSHIP (US) 1989-12-05 US disclosed
EP-0187768-A4 LIQUID CRYSTAL TEMPERATURE SENSOR AND MATERIALS. FERGASON JAMES L 1989-03-09 EP disclosed
EP-0187768-A1 LIQUID CRYSTAL TEMPERATURE SENSOR AND MATERIALS. FERGASON JAMES L 1986-07-23 EP disclosed
WO-1985005467-A1 LIQUID CRYSTAL TEMPERATURE SENSOR AND MATERIALS FERGASON JAMES L 1985-12-05 WO disclosed
US-4385844-A THERMOSENSITIVE NON-CHLOLESTERIC COMPOUND AND ALKYLBENZOATE LIQUID CRYSTALS BECTON, DICKINSON AND COMPANY (US) 1983-05-31 US disclosed
US-4296631-A AND METHOD OF MODIFYING THE HYSTERETIC BEHAVIOR BECTON, DICKINSON AND COMPANY (US) 1981-10-27 US disclosed
US-4140016-A CHOLESTERIC LIQUID CRYSTAL THERMOMETERS, BENZOIC ESTER DERIVATIVES BECTON, DICKINSON AND COMPANY (US) 1979-02-20 US disclosed
US-4037062-A Liquid crystal electromechanical transducer FERGASON, JAMES L. 1977-07-19 US disclosed