SCHEMBL8045007

SCHEMBL8045007

O=C1CCC(=O)N2C(=O)CCN12

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.31
BRD2 P25440 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10685413 1.00 BRD4 (0.31) BRD4BRD2ALDH1A1HTT
SCHEMBL1065591 0.83 BRD4 (0.44) BRD4BRD2ALDH1A1
SCHEMBL11560817 0.81 BRD4 (0.37) BRD4BRD2ALDH1A1
SCHEMBL558683 0.73 ALDH1A1 (0.42) BRD4BRD2ALDH1A1HTT
SCHEMBL11606022 0.69 POLB (0.47) ALDH1A1
SCHEMBL12450880 0.69 CHRM2 (0.39) BRD4BRD2ALDH1A1
SCHEMBL14559892 0.69 BRD4 (0.39) BRD4BRD2ALDH1A1
SCHEMBL20919753 0.67 CHRM2 (0.33) BRD4BRD2ALDH1A1
SCHEMBL15509629 0.65 CHRM2 (0.37) BRD4BRD2ALDH1A1HTT
SCHEMBL5418407 0.64 MEN1 (0.43) ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000030865-A ELECTROLUMINESCENCE DEVICE TOYOTA CENTRAL RES & DEV LAB INC 2000-01-28 JP disclosed