SCHEMBL558683

SCHEMBL558683

O=C1CCC(=O)N1N1C(=O)CCC1=O

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
HTT P42858 1/20 0.42
BRD4 O60885 1/20 0.33
BRD2 P25440 1/20 0.33
TRIM24 O15164 1/20 0.31
TRIM33 Q9UPN9 1/20 0.31
PARL Q9H300 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2308600 0.80 ALDH1A1 (0.39) ALDH1A1HTT
SCHEMBL5336393 0.76 TSHR (0.35) ALDH1A1HTT
SCHEMBL9020270 0.75
SCHEMBL27941 0.75
SCHEMBL10685413 0.73 BRD4 (0.31) ALDH1A1HTTBRD4BRD2
SCHEMBL8045007 0.73 BRD4 (0.31) ALDH1A1HTTBRD4BRD2
SCHEMBL15509629 0.73 CHRM2 (0.37) ALDH1A1HTTBRD4BRD2GAA
SCHEMBL5304972 0.73
Methane SCHEMBL14957784 0.72
SCHEMBL8630177 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116284784-B Preparation method of recyclable orthogonal dynamic covalent fluorescent polymer material 华东理工大学 2025-05-27 CN claimed
CN-119780436-A Antibody-nano diamond conjugate and preparation method and application thereof 浙江启真量子科技有限公司 2025-04-08 CN claimed
CN-117623438-A Composite microsphere for adsorbing water pollutants and application thereof 西北农林科技大学 2024-03-01 CN claimed
CN-117069735-A Method for efficiently synthesizing Rayleigh Lu Geli and application thereof 北京海美源医药科技有限公司 2023-11-17 CN claimed
CN-116479660-A Halamine antibacterial porous organic polymer-based composite fiber material, preparation and application 东华大学 2023-07-25 CN claimed
CN-116284784-A Preparation method of recyclable orthogonal dynamic covalent fluorescent polymer material 华东理工大学 2023-06-23 CN claimed
US-20140302051-A1 Biocompatible Hydrogel Polymer Formulations for the Controlled Delivery of Biomolecules MEDICUS BIOSCIENCES, LLC (US) 2014-10-09 US claimed
CN-100506867-C Polymer having charged units COMMW SCIENT IND RES ORG (AU) 2009-07-01 CN claimed
CN-1656133-A Polymer having charged units COMMW SCIENT IND RES ORG (AU) 2005-08-17 CN claimed
CN-115667215-B Broad-spectrum antiviral medicine for resisting coronavirus 堪萨斯州立大学研究基金会 2026-05-19 CN disclosed
CN-122029175-A Modified nucleotide for improving chain offset, preparation method and application thereof 深圳华大智造科技股份有限公司 2026-05-12 CN disclosed
CN-116284784-B Preparation method of recyclable orthogonal dynamic covalent fluorescent polymer material 华东理工大学 2025-05-27 CN disclosed
CN-114423758-B Antibacterial compounds 爱尔兰詹森科学公司 2025-05-27 CN disclosed
CN-119780436-A Antibody-nano diamond conjugate and preparation method and application thereof 浙江启真量子科技有限公司 2025-04-08 CN disclosed
US-4578474-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1986-03-25 US disclosed
US-4497953-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1985-02-05 US disclosed
EP-0042639-B1 AZIDO, IMIDO, AMIDO AND AMINO DERIVATIVES OF MERCAPTOACYL PROLINES AND PIPECOLIC ACIDS HAVING HYPOTENSIVE ACTIVITY E.R. Squibb & Sons, Inc. (US) 1984-08-22 EP disclosed
US-4390695-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1983-06-28 US disclosed
US-4310461-A HYPTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1982-01-12 US disclosed
US-3933507-A LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER AGFA-GEVAERT, A.G. (DT) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140302051-A1 Biocompatible Hydrogel Polymer Formulations for the Controlled Delivery of Biomolecules HMGB1, HDGF, CRYAA ALDH1A1 661/4885HTT 835/4885BRD4 509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.