Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.56 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.56 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | CES1 | P23141 | 4/20 | 0.38 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080772 | 0.90 | SOAT2 (0.50) | SOAT2ACAT1SOAT1HPGDCES2 | |
| SCHEMBL8043376 | 0.89 | SOAT2 (0.60) | SOAT2ACAT1SOAT1HPGDCES2 | |
| SCHEMBL9446297 | 0.82 | SOAT1 (0.53) | SOAT2ACAT1SOAT1HPGDMAPT | |
| SCHEMBL9446369 | 0.82 | SOAT1 (0.53) | SOAT2ACAT1SOAT1HPGDMAPT | |
| SCHEMBL9446324 | 0.82 | SOAT1 (0.53) | SOAT2ACAT1SOAT1HPGDMAPT | |
| SCHEMBL9446351 | 0.82 | SOAT1 (0.53) | SOAT2ACAT1SOAT1HPGDMAPT | |
| SCHEMBL9446337 | 0.82 | SOAT1 (0.53) | SOAT2ACAT1SOAT1HPGDMAPT | |
| SCHEMBL9446388 | 0.82 | SOAT1 (0.53) | SOAT2ACAT1SOAT1HPGDMAPT | |
| SCHEMBL9446291 | 0.82 | SOAT1 (0.53) | SOAT2ACAT1SOAT1HPGDMAPT | |
| SCHEMBL9446353 | 0.82 | SOAT1 (0.53) | SOAT2ACAT1SOAT1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874812-B1 | NOVEL 2,3,5-TRIMETHYL-4-HYDROXY ANILIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | PF MEDICAMENT (FR) | 2000-04-05 | — | — | EP | disclosed |
| US-5990173-A | ANTICHOLESTEROL AGENTS; TREATING ATHEROSCLEROSIS; ENZYME INHIBITORS OF ACYLCOENZYME A:CHOLESTEROL ACYLTRANSFERASE (ACAT) | PIERRE FABRE MEDICAMENT (FR) | 1999-11-23 | — | — | US | disclosed |