SCHEMBL8045210

SCHEMBL8045210

CCC(C)CCC1CCC(C2CCC(c3ccc(C(F)(F)F)c(F)c3)CC2)CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.39
EPHX2 P34913 3/20 0.34
PDE2A O00408 3/20 0.34
POLQ O75417 1/20 0.32
CHRM2 P08172 1/20 0.32
DRD2 P14416 1/20 0.32
CHRNB2 P17787 1/20 0.32
DRD4 P21917 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
DRD3 P35462 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
TMEM97 Q5BJF2 1/20 0.32
CYP2C9 P11712 1/20 0.32
TRPM8 Q7Z2W7 1/20 0.32
HTR2A P28223 1/20 0.31
MDM2 Q00987 1/20 0.31
CYP11B1 P15538 2/20 0.31
CYP11B2 P19099 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8051974 0.95 KDM1A (0.41) KDM1AEPHX2PDE2APOLQCHRM2
SCHEMBL8046206 0.88 CYP11B1 (0.38) KDM1ACYP11B1CYP11B2
SCHEMBL8034601 0.87 KIF11 (0.41) KDM1ACYP11B1CYP11B2
SCHEMBL8046193 0.85 DAO (0.37) KDM1AEPHX2PDE2ACYP2C9MDM2
SCHEMBL8045397 0.85 CYP11B1 (0.35) KDM1AEPHX2PDE2ACYP11B1CYP11B2
SCHEMBL8045285 0.85 KDM1A (0.34) KDM1AEPHX2PDE2APOLQTRPM8
SCHEMBL8961337 0.85 KDM1A (0.44) KDM1AEPHX2PDE2APOLQCHRM2
SCHEMBL8961279 0.85 KDM1A (0.44) KDM1AEPHX2PDE2APOLQCHRM2
SCHEMBL8961284 0.85 KDM1A (0.44) KDM1AEPHX2PDE2APOLQCHRM2
SCHEMBL8043937 0.85 KDM1A (0.40) KDM1AEPHX2PDE2APOLQCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0733692-B1 Liquid crystalline compound, liquid crystal composition containing the same, and display device CHISSO CORP (JP) 2000-06-14 EP disclosed
US-5714088-A TRIFLUOROMETHYL- OR -METHOXYPHENYL-SUBSTITUTED BRANCHED ALKYL-SUBSTITUTED CYCLOHEXANES; LARGE POSITIVE VALUE OF DIELECTRIC ANISOTROPY; VERY LOW VISCOSITY; HIGH VOLTAGE HOLDING RATIO(SPECIFIC RESISTANCE); UV STABILITY CHISSO CORPORATION (JP) 1998-02-03 US disclosed
CN-1140194-A Liquid crystalline compound having branched alkyl group at its side chain and liquid crystal composition containing the same CHISSO CORP (JP) 1997-01-15 CN disclosed
EP-0733692-A1 Liquid crystalline compound, liquid crystal composition containing the same, and display device Chisso Corporation (JP) 1996-09-25 EP disclosed