SCHEMBL8045285

SCHEMBL8045285

CCC(C)CCC1CCC(c2ccc(CCc3ccc(C(F)(F)F)c(F)c3)c(F)c2)CC1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.34
DAO P14920 1/20 0.34
MDM2 Q00987 2/20 0.33
POLQ O75417 1/20 0.32
HCRTR1 O43613 1/20 0.32
HCRTR2 O43614 1/20 0.32
PDE2A O00408 1/20 0.31
EPHX2 P34913 1/20 0.31
KCNH2 Q12809 1/20 0.30
FFAR1 O14842 1/20 0.30
TRPM8 Q7Z2W7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8046193 0.91 DAO (0.37) KDM1ADAOMDM2HCRTR1HCRTR2
SCHEMBL8053249 0.88 EPHX2 (0.35) KDM1ADAOMDM2HCRTR1HCRTR2
SCHEMBL8052323 0.88 MEN1 (0.34) DAOKCNH2
SCHEMBL8049058 0.88 DAO (0.30) DAO
SCHEMBL8748215 0.88 KDM1A (0.38) KDM1ADAOPOLQHCRTR1HCRTR2
SCHEMBL8051974 0.88 KDM1A (0.41) KDM1AMDM2POLQPDE2AEPHX2
SCHEMBL8043804 0.87 KDM1A (0.34) KDM1ADAOMDM2POLQHCRTR1
SCHEMBL8747905 0.86 KDM1A (0.36) KDM1ADAOPOLQHCRTR1HCRTR2
SCHEMBL8048717 0.86 KCNH2 (0.37) HCRTR1HCRTR2PDE2AEPHX2KCNH2
SCHEMBL8045210 0.85 KDM1A (0.39) KDM1AMDM2POLQPDE2AEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0733692-B1 Liquid crystalline compound, liquid crystal composition containing the same, and display device CHISSO CORP (JP) 2000-06-14 EP disclosed
US-5714088-A TRIFLUOROMETHYL- OR -METHOXYPHENYL-SUBSTITUTED BRANCHED ALKYL-SUBSTITUTED CYCLOHEXANES; LARGE POSITIVE VALUE OF DIELECTRIC ANISOTROPY; VERY LOW VISCOSITY; HIGH VOLTAGE HOLDING RATIO(SPECIFIC RESISTANCE); UV STABILITY CHISSO CORPORATION (JP) 1998-02-03 US disclosed
CN-1140194-A Liquid crystalline compound having branched alkyl group at its side chain and liquid crystal composition containing the same CHISSO CORP (JP) 1997-01-15 CN disclosed
EP-0733692-A1 Liquid crystalline compound, liquid crystal composition containing the same, and display device Chisso Corporation (JP) 1996-09-25 EP disclosed