Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043000 | 0.76 | DCUN1D1 (0.42) | DCUN1D1ALDH1A1RXFP1PKMKDM4E | |
| SCHEMBL4877279 | 0.70 | ALDH1A1 (0.38) | DCUN1D1ALDH1A1RXFP1KDM4EPPARG | |
| SCHEMBL197690 | 0.67 | ACHE (0.64) | DCUN1D1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30169568 | 0.67 | ACHE (0.64) | DCUN1D1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30354037 | 0.67 | ACHE (0.64) | DCUN1D1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5601772 | 0.65 | NPC1 (0.41) | DCUN1D1ALDH1A1NPSR1RXFP1PKM | |
| SCHEMBL6564122 | 0.64 | ACHE (0.60) | DCUN1D1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL842431 | 0.64 | ACHE (0.60) | DCUN1D1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Lithium SCHEMBL31260773 | 0.64 | ACHE (0.60) | DCUN1D1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8042822 | 0.64 | KDM4E (0.50) | ALDH1A1PKMKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |