Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034034 | 1.00 | ALDH1A1 (0.61) | ALDH1A1POLBNPSR1CYP2C9RAB9A | |
| SCHEMBL8046529 | 0.98 | ALDH1A1 (0.58) | ALDH1A1POLBNPSR1CYP2C9RAB9A | |
| SCHEMBL1719258 | 0.94 | ALDH1A1 (0.52) | ALDH1A1POLBNPSR1CYP2C9RAB9A | |
| SCHEMBL14557094 | 0.87 | ALDH1A1 (0.50) | ALDH1A1POLBNPSR1L3MBTL1GLS | |
| SCHEMBL6553986 | 0.85 | ALDH1A1 (0.73) | ALDH1A1POLBNPSR1CYP2C9RAB9A | |
| SCHEMBL31244838 | 0.85 | ALDH1A1 (0.73) | ALDH1A1POLBNPSR1CYP2C9RAB9A | |
| SCHEMBL22368217 | 0.85 | ALDH1A1 (0.73) | ALDH1A1POLBNPSR1CYP2C9RAB9A | |
| SCHEMBL6406054 | 0.83 | ALDH1A1 (0.69) | ALDH1A1POLBNPSR1CYP2C9RAB9A | |
| SCHEMBL5654025 | 0.79 | ALDH1A1 (0.41) | ALDH1A1POLBNPSR1TSHRGLS | |
| SCHEMBL11422899 | 0.78 | ALDH1A1 (0.63) | ALDH1A1POLBNPSR1CYP2C9RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |