Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FADS1 | O60427 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13818358 | 0.75 | MEN1 (0.48) | MEN1KMT2ANPC1RAB9ADDB1 | |
| SCHEMBL225262 | 0.73 | KMT2A (0.47) | MEN1KMT2ANPC1RAB9ADDB1 | |
| Water SCHEMBL2910884 | 0.72 | KMT2A (0.45) | MEN1KMT2ANPC1RAB9ADDB1 | |
| SCHEMBL6205439 | 0.71 | DDB1 (0.44) | MEN1KMT2ANPC1RAB9ADDB1 | |
| SCHEMBL8790545 | 0.71 | MEN1 (0.48) | MEN1KMT2ANPC1RAB9ADDB1 | |
| SCHEMBL17704774 | 0.70 | NPC1 (0.73) | MEN1KMT2ANPC1RAB9ADDB1 | |
| SCHEMBL30157963 | 0.69 | POLB (0.46) | MEN1KMT2ANPC1RAB9ADDB1 | |
| SCHEMBL18379593 | 0.69 | ALDH1A1 (0.46) | MEN1KMT2ANPC1RAB9ADDB1 | |
| SCHEMBL30209937 | 0.68 | TNKS (0.49) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL10447256 | 0.68 | ALDH1A1 (0.51) | MEN1KMT2ANPC1RAB9ADDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000063703-A1 | USE OF AZETIDINONE COMPOUNDS | SCHERING CORPORATION (US) | 2000-10-26 | — | — | WO | disclosed |