Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FADS1 | O60427 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL2910884 | 0.98 | KMT2A (0.45) | KMT2AMEN1NPC1RAB9ATSHR | |
| SCHEMBL6964905 | 0.88 | FADS1 (0.50) | KMT2AMEN1TSHRROCK2ALDH1A1 | |
| SCHEMBL8495437 | 0.84 | ATM (0.51) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8495439 | 0.84 | ATM (0.51) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4721528 | 0.81 | ROCK2 (0.62) | KMT2AMEN1NPC1RAB9ATSHR | |
| SCHEMBL9309143 | 0.78 | ROCK2 (0.52) | KMT2AMEN1NPC1RAB9ATSHR | |
| SCHEMBL7758080 | 0.78 | ROCK2 (0.36) | KMT2AMEN1NPC1RAB9ATSHR | |
| SCHEMBL1958248 | 0.77 | ROCK2 (0.51) | KMT2AMEN1NPC1RAB9ATSHR | |
| SCHEMBL7436193 | 0.74 | ALDH1A1 (0.45) | KMT2AMEN1NPC1RAB9ATSHR | |
| SCHEMBL3289329 | 0.73 | KMT2A (0.47) | KMT2AMEN1TSHRSMN1; SMN2DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4712959-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 2,3,4,5-TETRAHYDRO-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES AND THE USE THEREOF | Mirum Pharmaceuticals, Inc. (US) | 2026-03-25 | — | — | EP | claimed |
| WO-2024243023-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 2,3,4,5-TETRAHYDRO-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES AND THE USE THEREOF | MIRUM PHARMACEUTICALS, INC. (US) | 2024-11-28 | — | — | WO | claimed |
| US-8207146-B2 | Phenothiazine derivative having a double bond, method for the production thereof, and use thereof as a pharmaceutical | SANOFI-AVENTIS (FR) | 2012-06-26 | — | — | US | claimed |
| EP-2203448-B1 | PHENOTHIAZINE DERIVATIVE HAVING A DOUBLE BOND, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS A PHARMACEUTICAL | SANOFI AVENTIS (FR) | 2011-06-22 | — | — | EP | claimed |
| US-7956085-B2 | 1,4-benzothiepine 1,1-dioxide derivatives substituted by benzyl radicals, method for their preparation, pharmaceuticals comprising these compounds, and the use thereof | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2011-06-07 | — | — | US | claimed |
| US-20100261643-A1 | PHENOTHIAZINE DERIVATIVE HAVING A DOUBLE BOND, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS A PHARMACEUTICAL | SANOFI-AVENTIS (FR) | 2010-10-14 | — | — | US | claimed |
| US-20100035961-A1 | Novel 1,4-benzothiepine 1,1-dioxide derivatives substituted by benzyl radicals, method for their preparation, pharmaceuticals comprising these compounds, and the use thereof | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2010-02-11 | — | — | US | claimed |
| CN-100582092-C | Process for preparing diphenyl azetidinone derivatives | AVENTIS PHARMA GMBH | 2010-01-20 | — | — | CN | claimed |
| CN-101535326-A | Novel 1,4-benzothiepin-1,1-dioxide derivatives which are substituted with benzyl groups, method for producing drugs containing said compounds and use thereof | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-09-16 | — | — | CN | claimed |
| US-7563888-B2 | Process for the preparation of diphenyl azetidinone derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-07-21 | — | — | US | claimed |
| US-20070149501-A1 | PROCESS FOR THE PREPARATION OF DIPHENYL AZETIDINONE DERIVATIVES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-06-28 | — | — | US | claimed |
| CN-1956951-A | Method for producing diphenyl azetidinone derivatives | AVENTIS PHARMA GMBH (DE) | 2007-05-02 | — | — | CN | claimed |
| CN-1805926-A | Process for the preparation of trans-isomers of diphenylazetidinone derivatives | RANBAXY LAB LTD (IN) | 2006-07-19 | — | — | CN | claimed |
| EP-1626954-A2 | PROCESS FOR THE PREPARATION OF TRANS-ISOMERS OF DIPHENYLAZETIDINONE DERIVATIVES | RANBAXY LABORATORIES, LTD. (IN) | 2006-02-22 | — | — | EP | claimed |
| WO-2004099132-A2 | PROCESS FOR THE PREPARATION OF TRANS-ISOMERS OF DIPHENYLAZETIDINONE DERIVATIVES | RANBAXY LABORATORIES LIMITED (IN) | 2004-11-18 | — | — | WO | claimed |
| EP-4712959-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 2,3,4,5-TETRAHYDRO-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES AND THE USE THEREOF | Mirum Pharmaceuticals, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024243023-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 2,3,4,5-TETRAHYDRO-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES AND THE USE THEREOF | MIRUM PHARMACEUTICALS, INC. (US) | 2024-11-28 | — | — | WO | disclosed |
| WO-2002050068-A1 | DIPHENYL AZETIDINONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING THESE COMPOUNDS, AND THEIR USE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-06-27 | — | — | WO | disclosed |
| US-20020013501-A1 | Process for the preparation of hydroxy and amino compounds | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2002-01-31 | — | — | US | disclosed |
| EP-1167325-A1 | Process for preparing hydroxy and amino compounds | Consortium für elektrochemische Industrie GmbH (DE) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149501-A1 | PROCESS FOR THE PREPARATION OF DIPHENYL AZETIDINONE DERIVATIVES | CYP46A1, APOB, DHCR7 | KMT2A 1869/4885MEN1 1200/4885NPC1 22/4885 |
| US-20100261643-A1 | PHENOTHIAZINE DERIVATIVE HAVING A DOUBLE BOND, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS A PHARMACEUTICAL | QDPR, DYRK4, CLK4 | KMT2A 1077/4885MEN1 2839/4885NPC1 2308/4885 |
| US-20100035961-A1 | Novel 1,4-benzothiepine 1,1-dioxide derivatives substituted by benzyl radicals, method for their preparation, pharmaceuticals comprising these compounds, and the use thereof | BBOX1, CYP2E1, CYP3A4 | KMT2A 2699/4885MEN1 615/4885NPC1 482/4885 |
| US-20020013501-A1 | Process for the preparation of hydroxy and amino compounds | BCKDK, KHK, HRH1 | KMT2A 645/4885MEN1 1379/4885NPC1 3146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.