Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | RAMP3 | O60896 | 6/20 | 0.38 |
| ▸ | CALCR | P30988 | 6/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045402 | 1.00 | GRB2 (0.44) | GRB2OPRM1OPRK1XIAPF2 | |
| SCHEMBL29636207 | 0.91 | GRB2 (0.49) | GRB2OPRM1OPRK1XIAPRAMP3 | |
| SCHEMBL11763946 | 0.89 | GRB2 (0.51) | GRB2OPRM1OPRK1F2RAMP3 | |
| SCHEMBL11763927 | 0.89 | GRB2 (0.51) | GRB2OPRM1OPRK1F2RAMP3 | |
| SCHEMBL1247795 | 0.87 | OPRM1 (0.48) | GRB2OPRM1OPRK1F2RAMP3 | |
| SCHEMBL21043608 | 0.87 | OPRM1 (0.48) | GRB2OPRM1OPRK1F2RAMP3 | |
| SCHEMBL194515 | 0.87 | OPRM1 (0.48) | GRB2OPRM1OPRK1F2RAMP3 | |
| SCHEMBL1247799 | 0.87 | OPRM1 (0.48) | GRB2OPRM1OPRK1F2RAMP3 | |
| SCHEMBL7263725 | 0.87 | OPRM1 (0.48) | GRB2OPRM1OPRK1F2RAMP3 | |
| SCHEMBL12899263 | 0.87 | OPRM1 (0.48) | GRB2OPRM1OPRK1F2RAMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110492-A | A STABLE OIL-IN-WATER EMULSION HAVING A CONTINUOUS WATER PHASE AND A DISCONTINUOUS OIL PHASE AND CONTAINING, AS SOLE STABILIZING AGENT, A SMECTIC MESOPHASE VESICLES AND THEIR DISINTEGRATED FORMS TO PROVIDE AMPHIPHILE | JENNER BIOTHERAPIES, INC. (US) | 2000-08-29 | — | — | US | disclosed |
| WO-1998053799-A9 | IMMUNOGENIC COMPOSITIONS | JENNER BIOTHERAPIES INC (US) | 1999-05-14 | — | — | WO | disclosed |
| WO-1998053799-A2 | IMMUNOGENIC COMPOSITIONS | JENNER BIOTHERAPIES, INC. (US) | 1998-12-03 | — | — | WO | disclosed |