Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.56 |
| ▸ | CTSS | P25774 | 2/20 | 0.56 |
| ▸ | CTSB | P07858 | 2/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.52 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.52 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29437121 | 0.83 | SMN1; SMN2 (0.62) | CTSKCTSSCTSBCTSLSMN1; SMN2 | |
| SCHEMBL36611 | 0.82 | SMN1; SMN2 (0.61) | CTSKCTSSCTSBCTSLSMN1; SMN2 | |
| SCHEMBL8496964 | 0.82 | SMN1; SMN2 (0.61) | CTSKCTSSCTSBCTSLSMN1; SMN2 | |
| SCHEMBL10385459 | 0.81 | SMN1; SMN2 (0.60) | CTSKCTSSCTSBCTSLSMN1; SMN2 | |
| SCHEMBL10385461 | 0.81 | SMN1; SMN2 (0.60) | CTSKCTSSCTSBCTSLSMN1; SMN2 | |
| Hydroxyamine SCHEMBL9197242 | 0.81 | SMN1; SMN2 (0.60) | CTSKCTSSCTSBCTSLSMN1; SMN2 | |
| SCHEMBL8410203 | 0.80 | CTSK (0.62) | CTSKCTSSCTSBCTSLCAPN1 | |
| SCHEMBL9228658 | 0.80 | SMN1; SMN2 (0.59) | CTSKCTSSCTSBCTSLSMN1; SMN2 | |
| SCHEMBL9228661 | 0.80 | SMN1; SMN2 (0.59) | CTSKCTSSCTSBCTSLSMN1; SMN2 | |
| SCHEMBL12829139 | 0.80 | CTSK (0.72) | CTSKCTSSCTSBCTSLCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057362-A | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-02 | — | — | US | disclosed |