Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.52 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.52 |
| ▸ | F3 | P13726 | 2/20 | 0.52 |
| ▸ | TNKS | O95271 | 1/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27887485 | 0.88 | EGFR (0.56) | TDP1GLANPC1L3MBTL1HDAC3 | |
| SCHEMBL27970225 | 0.87 | EGFR (0.58) | TDP1GLANPC1L3MBTL1HDAC3 | |
| SCHEMBL7659599 | 0.85 | GLA (0.57) | TDP1GLANPC1L3MBTL1HDAC3 | |
| SCHEMBL574953 | 0.81 | ALDH1A1 (0.70) | TDP1GLANPC1L3MBTL1HDAC3 | |
| SCHEMBL574952 | 0.81 | ALDH1A1 (0.70) | TDP1GLANPC1L3MBTL1HDAC3 | |
| SCHEMBL907461 | 0.79 | HDAC3 (0.44) | TDP1GLANPC1L3MBTL1HDAC3 | |
| Cinnamic Acid SCHEMBL29010571 | 0.79 | HDAC3 (0.68) | TDP1GLANPC1L3MBTL1HDAC3 | |
| Butyric Acid SCHEMBL30510740 | 0.79 | ALDH1A1 (0.68) | TDP1GLANPC1L3MBTL1HDAC3 | |
| SCHEMBL29109648 | 0.78 | IAPP (0.45) | MAPTALDH1A1LMNASMN1; SMN2CES2 | |
| SCHEMBL2153308 | 0.78 | MAPT (0.73) | TDP1GLANPC1L3MBTL1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440324-B1 | Substituted beta-diketones and their use in the treatment of inflammatory bowel disease | ORION YHTYMAE OY (FI) | 2000-04-12 | — | — | EP | disclosed |