SCHEMBL8045800

SCHEMBL8045800

Cc1cc(C2=NC(=S)N=N2)sc1Cl

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8047004 0.82
SCHEMBL8047343 0.82 ABL1 (0.32)
SCHEMBL8044875 0.72
SCHEMBL9773341 0.72 DAO (0.48) DAO
SCHEMBL8044634 0.69 CYP2A6 (0.38)
SCHEMBL8044128 0.68
SCHEMBL8042926 0.62 MEN1 (0.34)
SCHEMBL8050845 0.62 KDM4E (0.31)
SCHEMBL8051719 0.62
SCHEMBL8049118 0.61 MAPT (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6080772-A 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY SUGEN, INC. (US) 2000-06-27 US disclosed