Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8051368 | 0.77 | MAPT (0.37) | MEN1ALDH1A1MAPTKMT2AL3MBTL1 | |
| SCHEMBL8042926 | 0.73 | MEN1 (0.34) | CYP2A6MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8050845 | 0.73 | KDM4E (0.31) | ALDH1A1 | |
| SCHEMBL8047343 | 0.72 | ABL1 (0.32) | — | |
| SCHEMBL8045800 | 0.69 | DAO (0.33) | — | |
| SCHEMBL9193008 | 0.68 | CYP2A6 (0.50) | CYP2A6HSD17B1HSD17B2MEN1ALDH1A1 | |
| SCHEMBL8044128 | 0.68 | — | — | |
| SCHEMBL8048177 | 0.64 | RAB9A (0.37) | MAPTKMT2AL3MBTL1PGR | |
| SCHEMBL13101504 | 0.63 | CYP2A6 (0.36) | CYP2A6HSD17B1HSD17B2MEN1ALDH1A1 | |
| SCHEMBL8043756 | 0.63 | ALDH1A1 (0.42) | CYP2A6ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |