Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050049 | 0.89 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL8050177 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL8050828 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL8041828 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL8051515 | 0.81 | HPGD (0.49) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL8043575 | 0.80 | USP7 (0.36) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL8042315 | 0.80 | KMT2A (0.46) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL8032670 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL8051230 | 0.79 | TP53 (0.46) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL8042692 | 0.79 | POLB (0.46) | ALDH1A1MEN1KMT2AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |