Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265027 | 0.93 | LMNA (0.41) | NPSR1LMNAATMMEN1KMT2A | |
| SCHEMBL7955204 | 0.89 | ATM (0.39) | NPSR1ATMMEN1KMT2AKDM4E | |
| SCHEMBL3262282 | 0.82 | KDR (0.34) | BUB1ALDH1A1 | |
| SCHEMBL7948913 | 0.81 | LMNA (0.41) | NPSR1LMNAATMKDM4EL3MBTL1 | |
| SCHEMBL8049800 | 0.76 | KDM4E (0.42) | NPSR1LMNAATMMEN1KMT2A | |
| SCHEMBL8049619 | 0.75 | KDM4E (0.39) | LMNAATMMEN1KMT2AKDM4E | |
| SCHEMBL13099802 | 0.75 | ALDH1A1 (0.39) | NPSR1LMNAATMMEN1KMT2A | |
| SCHEMBL13099805 | 0.74 | LMNA (0.42) | LMNAMEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL13099801 | 0.74 | APOBEC3A (0.44) | ATMMEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL3107285 | 0.72 | KDM4E (0.39) | NPSR1LMNAATMBUB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009038385-A2 | NOVEL COMPOUNDS HAVING INDAZOLE FRAMEWORKS, METHODS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHOONGWAE PHARMA CORPORATION (KR) | 2009-03-26 | — | — | WO | disclosed |