Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | SRC | P12931 | 2/20 | 0.59 |
| ▸ | CASP3 | P42574 | 2/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | GLS | O94925 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050097 | 0.90 | NPC1 (0.58) | RAB9ANPC1SRCCASP3SENP7 | |
| SCHEMBL8051149 | 0.90 | GLS (0.47) | RAB9ANPC1SRCCASP3SENP7 | |
| SCHEMBL8044422 | 0.89 | RAB9A (0.46) | RAB9ANPC1SRCCASP3SENP7 | |
| SCHEMBL8051385 | 0.89 | GLS (0.46) | RAB9ANPC1SRCCASP3SENP7 | |
| SCHEMBL8044862 | 0.88 | GLS (0.46) | RAB9ANPC1SRCCASP3SENP7 | |
| SCHEMBL8033853 | 0.88 | NPC1 (0.44) | RAB9ANPC1SRCCASP3SENP7 | |
| SCHEMBL8052179 | 0.87 | RAB9A (0.48) | RAB9ANPC1SRCCASP3SENP7 | |
| SCHEMBL8048704 | 0.87 | NPSR1 (0.45) | RAB9ANPC1SRCCASP3SENP7 | |
| SCHEMBL8044767 | 0.85 | NPSR1 (0.43) | RAB9ANPC1SRCCASP3SENP7 | |
| SCHEMBL8049839 | 0.84 | KMT2A (0.52) | RAB9ANPC1RXFP1GLSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |