SCHEMBL8046024

SCHEMBL8046024

CCC(C)CCC1CCC(CCc2ccc(-c3cc(F)c(C(F)(F)F)c(F)c3)cc2)CC1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.37
GRM2 Q14416 1/20 0.33
MAOB P27338 6/20 0.32
KIF11 P52732 1/20 0.32
MAOA P21397 1/20 0.31
FFAR4 Q5NUL3 5/20 0.31
RARB P10826 2/20 0.30
RARA P10276 1/20 0.30
RARG P13631 1/20 0.30
ACACB O00763 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8044840 0.89 AKR1C3 (0.33) GPR84GRM2
SCHEMBL8052160 0.88 KIF11 (0.47) KIF11
SCHEMBL8034250 0.87 DAO (0.33)
SCHEMBL8046553 0.86 FFAR4 (0.33) GPR84GRM2FFAR4
SCHEMBL8045321 0.86 CYP2C9 (0.34) GRM2ACACB
SCHEMBL8048726 0.85 DAO (0.33)
SCHEMBL8567647 0.85 MAOB (0.45) GPR84MAOBKIF11HRH3
SCHEMBL8046694 0.84 GPR84 (0.38) GPR84GRM2MAOBKIF11FFAR4
SCHEMBL8034592 0.83 EPHX2 (0.38) GRM2FFAR4
SCHEMBL8052420 0.83 SPHK1 (0.34) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0733692-B1 Liquid crystalline compound, liquid crystal composition containing the same, and display device CHISSO CORP (JP) 2000-06-14 EP disclosed
US-5714088-A TRIFLUOROMETHYL- OR -METHOXYPHENYL-SUBSTITUTED BRANCHED ALKYL-SUBSTITUTED CYCLOHEXANES; LARGE POSITIVE VALUE OF DIELECTRIC ANISOTROPY; VERY LOW VISCOSITY; HIGH VOLTAGE HOLDING RATIO(SPECIFIC RESISTANCE); UV STABILITY CHISSO CORPORATION (JP) 1998-02-03 US disclosed
EP-0733692-A1 Liquid crystalline compound, liquid crystal composition containing the same, and display device Chisso Corporation (JP) 1996-09-25 EP disclosed