Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029114 | 0.88 | KMT2A (0.54) | KMT2AMEN1USP2GAAALOX5 | |
| SCHEMBL8039047 | 0.88 | KMT2A (0.54) | KMT2AMEN1USP2GAAALOX5 | |
| SCHEMBL8029107 | 0.88 | KMT2A (0.54) | KMT2AMEN1USP2GAAALOX5 | |
| SCHEMBL5094098 | 0.83 | USP2 (0.54) | BRD4KMT2AMEN1USP2GAA | |
| SCHEMBL10679337 | 0.81 | BRD4 (0.45) | BRD4KMT2AMEN1USP2GAA | |
| SCHEMBL8029156 | 0.79 | PARP1 (0.51) | KMT2AMEN1ALOX5HSD17B10ALDH1A1 | |
| SCHEMBL7470264 | 0.79 | L3MBTL1 (0.59) | KMT2AMEN1USP2GAAALOX5 | |
| SCHEMBL17055863 | 0.79 | L3MBTL1 (0.59) | KMT2AMEN1USP2GAAALOX5 | |
| SCHEMBL18581866 | 0.78 | USP2 (0.56) | KMT2AMEN1USP2GAAALOX5 | |
| SCHEMBL18619321 | 0.78 | USP2 (0.53) | KMT2AMEN1USP2GAAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060769-C | 1,4-benzoxazine derivatives, pharmaceutical composition containing the same and use thereof | KENEBO LTD (JP) | 2001-01-17 | — | — | CN | disclosed |
| EP-0719766-B1 | 1,4-Benzoxazine derivative, pharmaceutical composition containing the same and use thereof | KANEBO LTD (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-5597820-A | CARDIOVASCULAR DISORDERS | KANEBO, LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| CN-1130183-A | 1,4-benzoxazine derivatives, pharmaceutical composition containing the same and use thereof | KANEBO LTD (JP) | 1996-09-04 | — | — | CN | disclosed |
| EP-0719766-A1 | 1,4-Benzoxazine derivative, pharmaceutical composition containing the same and use thereof | KANEBO LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |