Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 16/20 | 0.54 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046490 | 0.84 | FBP1 (0.55) | FBP1TRPM2 | |
| SCHEMBL7208139 | 0.69 | FBP1 (0.54) | FBP1TRPM2 | |
| SCHEMBL13741964 | 0.68 | FBP1 (1.00) | FBP1 | |
| SCHEMBL4955833 | 0.66 | FBP1 (0.65) | FBP1 | |
| SCHEMBL4955818 | 0.65 | FBP1 (0.52) | FBP1 | |
| SCHEMBL14237111 | 0.63 | FBP1 (0.61) | FBP1 | |
| SCHEMBL5368083 | 0.63 | FBP1 (0.65) | FBP1 | |
| SCHEMBL5368090 | 0.62 | FBP1 (0.54) | FBP1 | |
| SCHEMBL8051443 | 0.62 | FBP1 (0.67) | FBP1 | |
| SCHEMBL5363823 | 0.60 | FBP1 (0.51) | FBP1SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060182-A2 | NOVEL PRODRUGS FOR PHOSPHORUS-CONTAINING COMPOUNDS | Metabasis Therapeutics, Inc. (US) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999045016-A9 | NOVEL PRODRUGS FOR PHOSPHORUS-CONTAINING COMPOUNDS | METABASIS THERAPEUTICS INC (US) | 2000-03-02 | — | — | WO | disclosed |
| WO-1999045016-A2 | NOVEL PRODRUGS FOR PHOSPHORUS-CONTAINING COMPOUNDS | METABASIS THERAPEUTICS, INC. (US) | 1999-09-10 | — | — | WO | disclosed |