Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 17/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046435 | 0.84 | FBP1 (0.54) | FBP1TRPM2 | |
| SCHEMBL5732048 | 0.69 | ADORA2A (0.72) | FBP1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL5358382 | 0.64 | FBP1 (1.00) | FBP1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL6346450 | 0.64 | FBP1 (1.00) | FBP1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL5358021 | 0.64 | ADORA2A (0.69) | FBP1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL5364361 | 0.63 | ADORA2A (1.00) | FBP1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL5359008 | 0.63 | FBP1 (0.68) | FBP1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL5357844 | 0.62 | ADORA2A (0.73) | FBP1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL3120333 | 0.61 | HSP90AB1 (0.50) | ADORA2AADORA1 | |
| SCHEMBL1914306 | 0.61 | ADORA2A (0.71) | FBP1ADORA2AADORA1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060182-A2 | NOVEL PRODRUGS FOR PHOSPHORUS-CONTAINING COMPOUNDS | Metabasis Therapeutics, Inc. (US) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999045016-A2 | NOVEL PRODRUGS FOR PHOSPHORUS-CONTAINING COMPOUNDS | METABASIS THERAPEUTICS, INC. (US) | 1999-09-10 | — | — | WO | disclosed |