Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23620552 | 0.78 | HPGD (0.56) | HSD17B10HPGDHTTPDE3BPDE3A | |
| SCHEMBL12251819 | 0.69 | HSD17B10 (0.55) | HSD17B10HPGDHTTPDE3BPDE3A | |
| SCHEMBL19657538 | 0.67 | PDE3B (0.51) | HSD17B10HPGDHTTPDE3BPDE3A | |
| SCHEMBL5454832 | 0.64 | ALDH1A1 (0.50) | HSD17B10HPGDHTTALDH1A1KDM4E | |
| SCHEMBL30349792 | 0.64 | HSD17B10 (0.62) | HSD17B10HPGDHTTPDE3BPDE3A | |
| SCHEMBL13733156 | 0.64 | PIK3CD (0.47) | HSD17B10HPGDHTTPDE3BPDE3A | |
| SCHEMBL3513392 | 0.64 | HSD17B10 (1.00) | HSD17B10HPGDHTTPDE3BPDE3A | |
| SCHEMBL25407471 | 0.64 | HSD17B10 (0.62) | HSD17B10HPGDHTTPDE3BPDE3A | |
| SCHEMBL25057366 | 0.63 | HSD17B10 (0.44) | HSD17B10HPGDHTTGSK3BPIK3CD | |
| SCHEMBL23473313 | 0.63 | HSD17B10 (0.43) | HSD17B10HPGDHTTGSK3BPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143765-A | ENZYME IHIBITORS OF PROTEIN | SUGEN, INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |