Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 4/20 | 0.33 |
| ▸ | KDR | P35968 | 4/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.33 |
| ▸ | PTPRC | P08575 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052434 | 1.00 | HDAC1 (0.33) | HDAC1HDAC8AURKAKDRAURKB | |
| SCHEMBL8053515 | 0.85 | MAPT (0.39) | AURKAKDRAURKBPTPRCKDM4E | |
| SCHEMBL8046733 | 0.85 | MAPT (0.39) | AURKAKDRAURKBPTPRCKDM4E | |
| SCHEMBL8049234 | 0.85 | MAPT (0.39) | AURKAKDRAURKBPTPRCKDM4E | |
| SCHEMBL8052585 | 0.85 | MAPT (0.39) | AURKAKDRAURKBPTPRCKDM4E | |
| SCHEMBL8040104 | 0.83 | KMT2A (0.43) | AURKAKDRAURKBKDM4EL3MBTL1 | |
| SCHEMBL8052590 | 0.82 | MAPT (0.39) | AURKAKDRAURKBKDM4EAKT1 | |
| SCHEMBL8043998 | 0.82 | MAPT (0.39) | AURKAKDRAURKBKDM4EAKT1 | |
| SCHEMBL8044206 | 0.79 | AURKA (0.37) | HDAC1HDAC8AURKAKDRAURKB | |
| SCHEMBL8045596 | 0.79 | AURKA (0.37) | HDAC1HDAC8AURKAKDRAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085978-A1 | BRIDGED CARBOCYCLIC OXIME HEPATITIS C VIRUS SERINE PROTEASE INHIBITORS | ENANTA PHARCEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |