Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052585 | 0.89 | MAPT (0.39) | KMT2AMAPTSMN1; SMN2POLBHTT | |
| SCHEMBL8049234 | 0.89 | MAPT (0.39) | KMT2AMAPTSMN1; SMN2POLBHTT | |
| SCHEMBL8046733 | 0.89 | MAPT (0.39) | KMT2AMAPTSMN1; SMN2POLBHTT | |
| SCHEMBL8053515 | 0.89 | MAPT (0.39) | KMT2AMAPTSMN1; SMN2POLBHTT | |
| SCHEMBL8043998 | 0.88 | MAPT (0.39) | KMT2AMAPTSMN1; SMN2POLBHTT | |
| SCHEMBL8052590 | 0.88 | MAPT (0.39) | KMT2AMAPTSMN1; SMN2POLBHTT | |
| SCHEMBL8041854 | 0.87 | PDK2 (0.42) | PDK2PTPN11CA12CA1CA2 | |
| SCHEMBL8052434 | 0.83 | HDAC1 (0.33) | L3MBTL1KDM4EAURKAKDRAURKB | |
| SCHEMBL8046738 | 0.83 | HDAC1 (0.33) | L3MBTL1KDM4EAURKAKDRAURKB | |
| SCHEMBL8041866 | 0.72 | HTR3E (0.52) | KMT2AMAPTSMN1; SMN2POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085978-A1 | BRIDGED CARBOCYCLIC OXIME HEPATITIS C VIRUS SERINE PROTEASE INHIBITORS | ENANTA PHARCEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |