Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052716 | 0.85 | NISCH (0.40) | MAOBMMP9 | |
| SCHEMBL8045886 | 0.76 | NISCH (0.37) | NOTUMKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL8044042 | 0.74 | NISCH (0.46) | NOTUMALDH1A1HPGD | |
| SCHEMBL8045884 | 0.67 | NPC1 (0.44) | ALOX15KDM4EALDH1A1HPGD | |
| SCHEMBL9130147 | 0.66 | — | — | |
| SCHEMBL8052225 | 0.65 | — | — | |
| SCHEMBL8539618 | 0.61 | ATM (0.52) | L3MBTL1MAOBKDM4EALDH1A1HPGD | |
| SCHEMBL8539615 | 0.61 | ATM (0.52) | L3MBTL1MAOBKDM4EALDH1A1HPGD | |
| SCHEMBL2783537 | 0.61 | ALDH1A1 (0.43) | ALDH1A1HPGD | |
| SCHEMBL8034842 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661290-B1 | Compounds containing 1-aza-3-oxa-4-silacyclohex-1-enyl groups, and tautomers of said compounds | DOW CORNING ASIA LTD (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5446180-A | Compounds containing 1-aza-3-oxa-4-silacyclohex-1-enyl groups, and tautomers of said compounds | DOW CORNING ASIA LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0661290-A1 | Compounds containing 1-aza-3-oxa-4-silacyclohex-1-enyl groups, and tautomers of said compounds | DOW CORNING ASIA, Ltd. (JP) | 1995-07-05 | — | — | EP | disclosed |