SCHEMBL8047199

SCHEMBL8047199

CCC(C(=O)O)C(=O)C(=O)NN

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.35
CA1 P00915 1/20 0.35
CTSD P07339 1/20 0.34
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
SLC1A1 P43005 1/20 0.34
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALOX15 P16050 1/20 0.31
MAPK1 P28482 1/20 0.31
CHRM1 P11229 1/20 0.31
AKR1A1 P14550 1/20 0.31
CHRM3 P20309 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31
HRH1 P35367 1/20 0.31
DRD3 P35462 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8048134 0.79 FOLH1 (0.35) CA2CA1SLC1A3SLC1A2SLC1A1
SCHEMBL1047552 0.76 CA2 (0.47) CA2CA1CTSDSLC1A3SLC1A2
SCHEMBL3504770 0.72 CHRM1 (0.38) CA2SLC1A3SLC1A2SLC1A1ALDH1A1
Ethylmalonate SCHEMBL107241 0.71
SCHEMBL3226142 0.70 CHRM1 (0.36) CA2SLC1A3SLC1A2SLC1A1ALDH1A1
SCHEMBL1758553 0.70 CA1 (0.50) CA2CA1CTSDALDH1A1KDM4E
SCHEMBL5753839 0.70 TDP1 (0.36) CA2SLC1A3SLC1A2SLC1A1ALDH1A1
Ethylmalonate SCHEMBL9765245 0.68 HDAC1 (0.43) CA2SLC1A3SLC1A2SLC1A1ALDH1A1
Ethylmalonate SCHEMBL9118935 0.68 HDAC1 (0.43) CA2SLC1A3SLC1A2SLC1A1MEN1
Ethylmalonate SCHEMBL108554 0.68 HDAC1 (0.43) CA2SLC1A3SLC1A2SLC1A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0991772-A1 METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL VICINAL AMINOALCOHOLS Biocatalytics, Inc. (US) 2000-04-12 EP disclosed
US-5942644-A Precursors for the production of chiral vicinal aminoalcohols BIOCATALYTICS, INC. (US) 1999-08-24 US disclosed
WO-1998054350-A1 METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL VICINAL AMINOALCOHOLS BIOCATALYTICS, INC. (US) 1998-12-03 WO disclosed
US-5834261-A STEREOSPECIFIC REARRANGEMENT BIOSYNTHESIS BY MICROORGANISM BIOCATALYTICS, INC. (US) 1998-11-10 US disclosed