Ethylmalonate

Ethylmalonate

SCHEMBL9118935

CCC(C(=O)O)C(=O)O.[Ag].[Ag]

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.43
HDAC2 Q92769 2/20 0.43
CHRM1 P11229 1/20 0.43
AKR1A1 P14550 1/20 0.43
CHRM3 P20309 1/20 0.43
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
ADRA1A P35348 1/20 0.43
HRH1 P35367 1/20 0.43
DRD3 P35462 1/20 0.43
SLC6A3 Q01959 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CA2 P00918 1/20 0.42
MAPK1 P28482 1/20 0.42
FFAR3 O14843 2/20 0.41
SLC1A3 P43003 1/20 0.40
SLC1A2 P43004 1/20 0.40
SLC1A1 P43005 1/20 0.40
TP53 P04637 1/20 0.39
ENPEP Q07075 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylmalonate SCHEMBL28145639 1.00 HDAC1 (0.43) HDAC1HDAC2CHRM1AKR1A1CHRM3
Ethylmalonate SCHEMBL107241 0.96
Ethylmalonate SCHEMBL9765245 0.93 HDAC1 (0.43) HDAC1HDAC2CHRM1AKR1A1CHRM3
Ethylmalonate SCHEMBL83437 0.93 HDAC1 (0.43) HDAC1HDAC2CHRM1AKR1A1CHRM3
Ethylmalonate SCHEMBL29018396 0.93 HDAC1 (0.43) HDAC1HDAC2CHRM1AKR1A1CHRM3
Ethylmalonate SCHEMBL108554 0.93 HDAC1 (0.43) HDAC1HDAC2CHRM1AKR1A1CHRM3
Ethylmalonate SCHEMBL108039 0.93 HDAC1 (0.43) HDAC1HDAC2CHRM1AKR1A1CHRM3
Ethylmalonate SCHEMBL3157979 0.93 HDAC1 (0.43) HDAC1HDAC2CHRM1AKR1A1CHRM3
Ethylmalonate SCHEMBL5236397 0.93 HDAC1 (0.43) HDAC1HDAC2CHRM1AKR1A1CHRM3
Ethylmalonate SCHEMBL27797215 0.93 HDAC1 (0.43) HDAC1HDAC2CHRM1AKR1A1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1063753-C Method for preparing platinum compound SUNKYONG IND LTD (KR) 2001-03-28 CN disclosed
CN-1204650-A Method for preparing platinum compound SUNKYONG IND LTD (KR) 1999-01-13 CN disclosed
CN-1038590-C Process for preparing platinum complexes SUNKYONG IND LTD (KR) 1998-06-03 CN disclosed
US-5395947-A Antitumor agents SUNKYONG INDUSTRIES, LTD. (KR) 1995-03-07 US disclosed
CN-1065274-A Platinum complex and preparation method thereof SUNKYONG IND LTD (KR) 1992-10-14 CN disclosed