SCHEMBL8047271

SCHEMBL8047271

CC(C)COc1ccc(CC[O])cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACACB O00763 5/20 0.52
NR1H4 Q96RI1 2/20 0.47
MAPT P10636 3/20 0.46
MEN1 O00255 1/20 0.46
ALOX12 P18054 1/20 0.46
KMT2A Q03164 1/20 0.46
ALDH1A1 P00352 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TARBP2 Q15633 1/20 0.44
LMNA P02545 1/20 0.44
POLB P06746 2/20 0.42
HPGD P15428 2/20 0.42
XBP1 P17861 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KDM4E B2RXH2 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
ADRB2 P07550 2/20 0.41
ADRB1 P08588 2/20 0.41
NR3C1 P04150 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20780568 0.86 ACACB (0.50) ACACBNR1H4MAPTMEN1ALOX12
SCHEMBL8048419 0.84 MAPT (0.49) ACACBNR1H4MAPTMEN1ALOX12
SCHEMBL123415 0.81 MAPT (0.55) ACACBNR1H4MAPTMEN1ALOX12
SCHEMBL20739975 0.81 ACACB (0.49) ACACBNR1H4MAPTMEN1ALOX12
SCHEMBL11157593 0.81 TAAR1 (0.57) ACACBLMNA
SCHEMBL8047274 0.81 ACACB (0.52) ACACBNR1H4MAPTMEN1ALOX12
SCHEMBL20175352 0.80 ACACB (0.46) ACACBMAPTMEN1ALOX12KMT2A
SCHEMBL15114294 0.79 LMNA (0.57) ACACBNR1H4MAPTMEN1ALOX12
SCHEMBL10284902 0.79 S1PR1 (0.49) ACACBMAPTMEN1ALOX12KMT2A
SCHEMBL19771016 0.79 ACACB (0.48) ACACBMAPTMEN1ALOX12KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6106999-A SENSITIVITY TO GENERAL-PURPOSE VISIBLE LIGHT LASER, SO THAT HIGH-SPEED SCANNING EXPOSURE IS POSSIBLE BY LASER, AND EXTREMELY FINE HIGH RESOLUTION CAN BE OBTAINED; CAN BE USED FOR COATING OR PRINTING UNDER SAFELIGHT IRRADIATING CONDITIONS MITSUI CHEMICALS (JP) 2000-08-22 US disclosed