⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8015136 | 0.86 | HIF1A (0.38) | — | |
| SCHEMBL8014637 | 0.85 | MAPT (0.39) | — | |
| SCHEMBL4161786 | 0.81 | — | — | |
| SCHEMBL2133471 | 0.79 | — | — | |
| SCHEMBL27747322 | 0.78 | — | — | |
| SCHEMBL287670 | 0.78 | — | — | |
| SCHEMBL1260681 | 0.78 | — | — | |
| SCHEMBL18877268 | 0.77 | PPARG (0.36) | — | |
| SCHEMBL18879326 | 0.77 | ALOX15 (0.52) | — | |
| SCHEMBL1973808 | 0.77 | PPARG (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092274-A2 | ENDOCYTIC AGENTS | BIOVENTURES, LLC (US) | 2024-05-02 | — | — | WO | disclosed |
| WO-2024015565-A1 | METHODS OF PREPARING AN ISOINDOLINONE DERIVATIVE AND CRYSTAL FORMS THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | WO | disclosed |
| WO-2022068933-A1 | COMPOUNDS AND METHODS OF TREATING DISEASES | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-07 | — | — | WO | disclosed |
| US-8716314-B2 | Isotopologues of thalidomide | CELGENE CORPORATION (US) | 2014-05-06 | — | — | US | disclosed |
| WO-2012059680-A2 | PROCESS FOR THE PREPARATION OF IMIDES, OF DERIVATIVES THEREOF AND USES | RHODIA OPERATIONS (FR) | 2012-05-10 | — | — | WO | disclosed |
| EP-0788479-B1 | SUBSTITUTED PHTHALIMIDO-CINNAMIC ACID DERIVATIVES WITH HERBICIDAL EFFECT | BASF AG (DE) | 2000-04-19 | — | — | EP | disclosed |
| EP-0939078-A2 | Substituted phthalimido-cinnamic acid derivatives with herbicidal activity | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-01 | — | — | EP | disclosed |
| US-5707937-A | AGRICULTURAL HERBICIDES, DESICCANTS, DEFOLIANTS, HARVESTING AIDS | BASF AKTIENGESELLSCHAFT (DE) | 1998-01-13 | — | — | US | disclosed |
| EP-0788479-A1 | SUBSTITUTED PHTHALIMIDO-CINNAMIC ACID DERIVATIVES WITH HERBICIDAL EFFECT | BASF AKTIENGESELLSCHAFT (DE) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996014298-A1 | SUBSTITUTED PHTHALIMIDO-CINNAMIC ACID DERIVATIVES WITH HERBICIDAL EFFECT | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-17 | — | — | WO | disclosed |