SCHEMBL8015136

SCHEMBL8015136

CC(CCCC=O)C(N)=O

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.38
TSHR P16473 3/20 0.37
CA1 P00915 3/20 0.33
CA2 P00918 1/20 0.33
LTA4H P09960 1/20 0.33
MAPT P10636 2/20 0.33
ALDH1A1 P00352 1/20 0.33
TRPV1 Q8NER1 2/20 0.32
BLM P54132 1/20 0.32
GABRR1 P24046 2/20 0.32
FAAH O00519 2/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8014637 0.94 MAPT (0.39) HIF1ATSHRCA1CA2LTA4H
SCHEMBL8048065 0.86
SCHEMBL4329013 0.83 CA1 (0.33) CA1CA2LTA4HMAPTALDH1A1
SCHEMBL8017524 0.82 LTA4H (0.30) LTA4H
SCHEMBL15340966 0.81 BLM (0.44) CA1CA2LTA4HBLMGABRR1
SCHEMBL8259830 0.81 MAPT (0.38) TSHRCA1CA2LTA4HMAPT
SCHEMBL16629081 0.81 MAPT (0.38) TSHRCA1CA2LTA4HMAPT
SCHEMBL3123520 0.81 MAPT (0.38) TSHRCA1CA2LTA4HMAPT
SCHEMBL1260682 0.80 HIF1A (0.39) HIF1ATSHRCA1LTA4HMAPT
SCHEMBL5076969 0.80 BLM (0.52) HIF1ATSHRCA1LTA4HBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6117822-A AS HERBICIDES AND PLANT DESICCANTS AND/OR DEFOLIANTS BASF AKTIENGESELLSCHAFT (DE) 2000-09-12 US disclosed
EP-0788479-B1 SUBSTITUTED PHTHALIMIDO-CINNAMIC ACID DERIVATIVES WITH HERBICIDAL EFFECT BASF AG (DE) 2000-04-19 EP disclosed
EP-0939078-A2 Substituted phthalimido-cinnamic acid derivatives with herbicidal activity BASF AKTIENGESELLSCHAFT (DE) 1999-09-01 EP disclosed
US-5807807-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-09-15 US disclosed
US-5707937-A AGRICULTURAL HERBICIDES, DESICCANTS, DEFOLIANTS, HARVESTING AIDS BASF AKTIENGESELLSCHAFT (DE) 1998-01-13 US disclosed
EP-0788479-A1 SUBSTITUTED PHTHALIMIDO-CINNAMIC ACID DERIVATIVES WITH HERBICIDAL EFFECT BASF AKTIENGESELLSCHAFT (DE) 1997-08-13 EP disclosed
WO-1996014298-A1 SUBSTITUTED PHTHALIMIDO-CINNAMIC ACID DERIVATIVES WITH HERBICIDAL EFFECT BASF AKTIENGESELLSCHAFT (DE) 1996-05-17 WO disclosed