Sugi Predict

Sugi Predict / Compounds / Coenzyme_A

Coenzyme_A

Coenzyme_A

SCHEMBL8048120

CC(C)(COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)O)[C@@H](O)C(=O)NCCC(=O)NCCS.O=C(O)CCC(=O)CC(=O)O

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ AURKA O14965 2/20 0.90
▸ CHAT P28329 2/20 0.90
▸ NAA50 Q9GZZ1 2/20 0.90
▸ EP300 Q09472 2/20 0.90
▸ KAT2B Q92831 1/20 0.90
▸ KAT5 Q92993 1/20 0.90

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17856796 0.95 EP300 (0.88) AURKACHATNAA50EP300KAT2B
SCHEMBL14124919 0.95 EP300 (0.86) AURKACHATNAA50EP300KAT2B
Coenzyme_A SCHEMBL18682057 0.95 EP300 (1.00) AURKACHATNAA50EP300KAT2B
Coenzyme_A SCHEMBL18682056 0.95 EP300 (1.00) AURKACHATNAA50EP300KAT2B
Coenzyme_A SCHEMBL13500623 0.95 EP300 (1.00) AURKACHATNAA50EP300KAT2B
Coenzyme_A SCHEMBL26752 0.95 EP300 (1.00) AURKACHATNAA50EP300KAT2B
Coenzyme_A SCHEMBL18033983 0.95 EP300 (1.00) AURKACHATNAA50EP300KAT2B
Coenzyme_A SCHEMBL18675521 0.95 EP300 (1.00) AURKACHATNAA50EP300KAT2B
Coenzyme_A SCHEMBL26753 0.95 EP300 (1.00) AURKACHATNAA50EP300KAT2B
Coenzyme_A SCHEMBL18180012 0.95 EP300 (1.00) AURKACHATNAA50EP300KAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114728871-A Microorganisms and methods for reducing by-products 基因组股份公司 2022-07-08 — — CN disclosed
US-6060241-A AMINO ACID SEQUENCE OF COENZYME A TRANSFERASE OR THIOLASE OR IMMUNOGENIC FRAGMENT FROM HELICOBACTER CAPABLE OF PROPAGATING IN HUMAN STOMACH; FOR SCREENING THERAPIES AND ENZYME INHIBITORS KIETA HOLDING SA (CH) 2000-05-09 — — US disclosed
EP-0904381-A2 COMPOSITIONS AND METHODS RELATING TO DRUG DISCOVERY AND DETECTION AND TREATMENT OF GASTROINTESTINAL DISEASES Kieta Holding S.A. (CH) 1999-03-31 — — EP disclosed
WO-1997038110-A2 COMPOSITIONS AND METHODS RELATING TO DRUG DISCOVERY AND DETECTION AND TREATMENT OF GASTROINTESTINAL DISEASES KIETA HOLDING S.A. (CH) 1997-10-16 — — WO disclosed
Send feedback