Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL9134499 | 0.92 | KMT2A (0.42) | CYP3A4LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL94000 | 0.90 | ALDH1A1 (0.47) | CYP3A4LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL29421638 | 0.90 | ALDH1A1 (0.47) | CYP3A4LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL19002230 | 0.84 | CYP3A4 (0.41) | CYP3A4LMNAALDH1A1TP53TSHR | |
| SCHEMBL29520654 | 0.83 | CYP3A4 (0.46) | CYP3A4LMNAALDH1A1TP53TSHR | |
| SCHEMBL328909 | 0.83 | CYP3A4 (0.46) | CYP3A4LMNAALDH1A1TP53TSHR | |
| SCHEMBL21748422 | 0.82 | KMT2A (0.41) | CYP3A4ALDH1A1KMT2AMEN1PABPC1 | |
| SCHEMBL10587657 | 0.82 | CD44 (0.38) | CYP3A4LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL21065758 | 0.81 | CYP3A4 (0.44) | CYP3A4LMNAALDH1A1TP53TSHR | |
| Lithium Ion SCHEMBL19732706 | 0.81 | CYP3A4 (0.44) | CYP3A4LMNAALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130252890-A1 | 6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, PHARMACEUTICAL PREPARATIONS COMPRISING THEM, AND THE USE THEREOF FOR PRODUCTION OF MEDICAMENTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-09-26 | — | — | US | claimed |
| US-5475140-A | Process for producing N,N-disubstituted p-phenylenediamine derivative sulfate | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-12 | — | — | US | claimed |
| EP-2841592-A1 | COMPOSITIONS AND METHODS FOR IN VITRO DIAGNOSTIC TESTS INCLUDING SULFONIC ACID | Surmodics IVD, Inc. (US) | 2015-03-04 | — | — | EP | disclosed |
| US-20130252890-A1 | 6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, PHARMACEUTICAL PREPARATIONS COMPRISING THEM, AND THE USE THEREOF FOR PRODUCTION OF MEDICAMENTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-09-26 | — | — | US | disclosed |
| WO-2013142758-A1 | COMPOSITIONS AND METHODS FOR IN VITRO DIAGNOSTIC TESTS INCLUDING SULFONIC ACID | SURMODICS, INC. (US) | 2013-09-26 | — | — | WO | disclosed |
| CN-101443311-A | 1H-indol-5-yl-piperazin-1-yl-methanone derivatives | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | CN | disclosed |
| CN-100378090-C | Substituted dioxopentacyclic derivative and its use in preparing neuro regulator | POISON MEDICINE INST ACADEMY O (CN) | 2008-04-02 | — | — | CN | disclosed |
| CN-1683365-A | Substituted dioxopentacyclic derivative and its use in preparing neuro regulator | POISON MEDICINE INST ACADEMY O (CN) | 2005-10-19 | — | — | CN | disclosed |
| EP-1003564-A1 | SOFT ORTHOPEDIC CASTING ARTICLE WITH REINFORCEMENT SYSTEM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-05-31 | — | — | EP | disclosed |
| US-5913840-A | Soft orthopedic casting article with reinforcement system | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-06-22 | — | — | US | disclosed |
| WO-1999008725-A1 | SOFT ORTHOPEDIC CASTING ARTICLE WITH REINFORCEMENT SYSTEM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-02-25 | — | — | WO | disclosed |
| EP-0677049-A1 | QUINAZOLINE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1995-10-18 | — | — | EP | disclosed |
| US-5428137-A | Useful in coloring almost all water-immiscible organic liquids, such as fuel oils, molten plastics, synthetic fiber spinning solutions and thermal transfer inks | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1995-06-27 | — | — | US | disclosed |
| WO-1994014795-A1 | QUINAZOLINE DERIVATIVES | YUHAN CORPORATION (KR) | 1994-07-07 | — | — | WO | disclosed |
| EP-0553858-A1 | Monoazo compound and dense solution thereof | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-4295853-A | EXTRACTING LIPOPEROXIDE FROM BLOOD OR SERUM, OXIDIZABLE COLOR REAGENT, COMPOUND OF MULTIVALENT METAL | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1981-10-20 | — | — | US | disclosed |
| US-4197125-A | MERCAPTO-CONTAINING ESTER IN ACTIVATING LAYER, UNSATURATED POLYURETHANE, VINYL MONOMER, PHOTOPOLYMERIZATION | TEIJIN LIMITED (JP) | 1980-04-08 | — | — | US | disclosed |
| US-4039529-A | Cycloaliphatic dicarbonyl containing azo dyestuffs | CIBA-GEIGY AG (CH) | 1977-08-02 | — | — | US | disclosed |
| US-3971771-A | DYES FOR POLYESTERS | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | disclosed |
| US-3950287-A | CURING, AMINES, FREE RADICAL CATALYSTS | ASHLAND OIL, INC. (US) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130252890-A1 | 6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, PHARMACEUTICAL PREPARATIONS COMPRISING THEM, AND THE USE THEREOF FOR PRODUCTION OF MEDICAMENTS | CYP19A1, SHBG, ESR2 | CYP3A4 534/4885LMNA 683/4885ALDH1A1 465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.